What is Omeprazole DR
Omeprazole
Delayed-Release Capsules is a substituted benzimidazole,
5-methoxy-2-[[(4-methoxy3, 5-dimethyl-2-pyridinyl) methyl]
sulfinyl]-1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C17H19N3O3S,with a molecular weight of 345.42.
Omeprazole is
supplied as delayed-release capsules for oral administration. Each
delayed-release capsule contains either 10 mg, 20 mg or 40 mg of omeprazole in
the form of enteric-coated granules with the following inactive ingredients:
cellulose, disodium hydrogen phosphate, hydroxypropyl cellulose, hypromellose,
lactose, mannitol, sodium lauryl sulfate and other ingredients
Omeprazole is a white
to off-white crystalline powder that melts with decomposition at about 155°C.
It is a weak base, freely soluble in ethanol and methanol, and slightly soluble
in acetone and isopropanol and very slightly soluble in water.The stability of
omeprazole is a function of pH; it is rapidly degraded in acid media, but has
acceptable stability under alkaline conditions.
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