Phenazopyridine
Class:Urinary tract analgesic
Mechanism of action
Phenazopyridine is
excreted in the urine where it exerts a topical analgesic action on urinary
tract mucosa through an unknown mechanism.
Pharmacokinetics
Metabolism:in the
liver and other tissues.Elimination:in urine(where it exert its action).Half
life:approx.13.5 hours.
Indications
Symptomatic relief of
pain,urinary burning,itching,frequency and urgency in association with urinary
tract infection or following urologic procedures.
Contraindications
Hypersensitivity to
phenazopyridine or any component;kidney or liver diseases.
Side effects
Headache,nausea,vomiting,diarrhea,rash,pruritis,discolouration
and hypersensitivity,methaemoglobinaemia,potential haemolytic agent in G6PD
deficiency.
Pregnancy
Pregnancy risk factor
B.
Dosage
Adults:200mg (2
tablets) 3 times daily with or after meals for 2 days when used concomitantly
with an antibacterial agent.Children:12mg/kg/day.
Brands
Tabs.Uropyrine 100mg.
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